Science and Research Studies | Medicinal Mushrooms and Herbs - Teelixir

The Science



Astragalus Root

Scientific Studies of Astragalus root (Astragalus membranaceus).

1.) Flavonoids (polyphenols) from Astragalus membranaceus.
2.) Anti-tumor effects of Astragalus.
3.) Astragaloside IV inhibits progression of lung cancer by mediating immune function of Tregs and CTLs by interfering with IDO.
4.) Astragaloside IV alleviates early brain injury following experimental subarachnoid hemorrhage in rats.
5.) Protective effects of astragaloside IV against ovalbumin-induced lung inflammation.
6.) Astragaloside IV prevents acute kidney injury in two rodent models by inhibiting oxidative stress and apoptosis pathways.
7.) Mitochondrial Protection and Anti-aging Activity of Astragalus Polysaccharides.
8.) The mechanism of astragaloside IV promoting sciatic nerve regeneration.
9.) Astragalus saponins affect proliferation, invasion and apoptosis of gastric cancer BGC-823 cells.
10.) Astragalus membranaceus Anti-Diabetic Research: Pharmacological Effects of Its Phytochemical Constituents.
11.) Cycloastragenol is a potent telomerase activator in neuronal cells: implications for depression management.
12.) Astragalus membranaceus Inhibits Inflammation.
13.) An in vivo molecular response analysis of colorectal cancer treated with Astragalus membranaceus extract.
14.) Effects of astragalus injection on the TGFβ/Smad pathway in the kidney in type 2 diabetic mice.
15.) Astragalus membranaceus modulates Th1/2 immune balance and activates PPARγ in a murine asthma model.
16.) The effects of Astragalus membranaceus on oxygen consumption in the intestine.
17.) In vitro and in vivo anti-tumor effects of Astragalus membranaceus.
18.) Reducing fatigue of athletes following oral administration of huangqi.
19.) Effect of Astragalus membranaceus in rats on peripheral nerve regeneration: in vitro and in vivo studies.
20.) The Antioxidant Effects of Radix Astragali (Astragalus membranaceus and Related Species).
21.) Anti-hepatitis B virus activities of astragaloside IV.
22.) Astragaloside IV attenuates hypoxia-induced cardiomyocyte damage in rats by upregulating superoxide dismutase-1 levels.
Find more scientific studies available at PubMed.

Chaga Mushroom

Scientific Studies of Chaga Mushroom (Inonotus obliquus).

1.) Immunostimulating Activity by Polysaccharides Isolated from Fruiting Body of Inonotus obliquus.
2.) Continuous intake of the Chaga mushroom (Inonotus obliquus) aqueous extract suppresses cancer progression and maintains body temperature in mice.
3.) Ergosterol peroxide from Chaga mushroom (Inonotus obliquus) exhibits anti-cancer activity by down-regulation of the β-catenin pathway in colorectal cancer.
4.) Anticancer effects of fraction isolated from fruiting bodies of Chaga medicinal mushroom.
5.) Antitumor activity and structure characterization of ethanol extracts from wild and cultivated Chaga medicinal mushroom.
6.) Alcohol extract of Chaga and its effects on colon cancer cells.
7.) Anticancer activity of subfractions containing pure compounds of Chaga mushroom (Inonotus obliquus) extract.
8.) Anticancer properties of the water extract of Inonotus [corrected] obliquus by induction of apoptosis in melanoma B16-F10 cells.
9.) Chaga mushroom extract inhibits oxidative DNA damage in lymphocytes of patients with inflammatory bowel disease.
10.) Immunomodulatory Activity of the Water Extract from Medicinal Mushroom Inonotus obliquus.
11.) Chaga and its anti-viral effects.
12.) Chaga and its anti-inflammatory effects.
13.) Aqueous extract of Inonotus obliquus ameliorates acute inflammation in dextran sulfate sodium (DSS)-induced colitis.
14.) Hepatoprotective Activity of Chaga.
15.) Anti-allergic Activity of Chaga.
16.) Anti-herpetic Activity of Chaga.

Find more scientific studies available at PubMed.


Cordyceps Mushroom

Scientific Studies of Cordyceps Mushroom (Cordyceps sinensis).

1.) A Systematic Review of Cordyceps Sinensis and Related Bioactive Ingredients.
2.) Medicinal Potential of Cordyceps sinensis.
3.) Cordyceps sinensis-based supplement boosts aerobic exercise.
4.) Cordyceps sinensis ameliorates exhaustive exercise-induced oxidative stress.
5.) Cordyceps sinensis improves exercise endurance capacity.
6.) Improving Training Condition Assessment in Endurance Cyclists using Cordyceps sinensis.
7.) Immunomodulatory and antioxidant activity of Cordyceps sinensis.
8.) Pharmacological basis of "Yin-nourishing" and "Yang-invigorating" actions of Cordyceps sinensis.
9.) Cordyceps sinensis can Improve Asthma Symptoms, Lung function, and Inflammatory Profile.
10.) Cordyceps sinensis can inhibit cigarette smoke extract-induced senescence in human bronchial epithelial cells.
11.) Cordyceps sinensis for treating chronic Kidney disease.
12.) Protective effect of Cordyceps sinensis in Liver diseases.
13.) Protective roles of Cordyceps sinensis on lung fibrosis.
14.) Potential of treating hypertension with Cordyceps sinensis.
15.) Cordyceps sinensis and Inflammation.
16.) Effect of Cordyceps sinensis (CS-4) on exercise performance in healthy elderly subjects.
17.) Phytochemical and antimicrobial activities of Cordyceps sinensis.

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Eleuthero Root (Siberian Ginseng)

Scientific Studies of Eleuthero root (Eleutherococcus senticosus; Acanthopanax senticosus).

1.) Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress-Protective Activity.
2.) Effects of Siberian Ginseng (Eleutherococcus senticosus) on elderly quality of life.
3.) Medicinal Plants in Therapy: Antioxidant Activities.
4.) Effects of Eleutherococcus senticosus Cortex on Recovery from the Forced Swimming Test and Fatty Acid β-Oxidation in the Liver and Skeletal Muscle of mice.
5.) Eleutherococcus senticosus as an adaptogen: a closer look.
6.) The effects of Acanthopanax senticosus extract on bone turnover and bone mineral density in Korean postmenopausal women.
7.) The effects of A. senticosus supplementation on serum lipid profiles, biomarkers of oxidative stress, and lymphocyte DNA damage in postmenopausal women.
8.) The influence of active components of Eleutherococcus senticosus on cellular defence and physical fitness in man.
9.) Effect of Eleutherococcus senticosus on submaximal and maximal exercise performance.
10.) The effect of Eleutheroside E on behavioral alterations in murine sleep deprivation stress model.
11.) The effect of eight weeks of supplementation with Eleutherococcus senticosus on endurance capacity and metabolism in humans.
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He Shou Wu Root (Prepared)

Scientific Studies of He Shou Wu (Polygonum multiflorum).

1.) Polygonum multiflorum root extract as a potential candidate for treatment of early graying hair.
2.) Mechanistic Studies on the Use of Polygonum multiflorum for the Treatment of Hair Graying.
3.) Lipase Inhibitory Activity of Polygonum Multiflorum.
4.) Nuclear Factor Kappa B Activation and Peroxisome Proliferator-activated Receptor Transactivational Effects of Polygonum multiflorum.
5.) Enhancement of antioxidant activity and anti-lipid peroxidation of Polygonum multiflorum.
6.) Effects of Polygonum multiflorum Extracts on Ovariectomy Induced Osteopenia in Mice.
7.) Polygonum multiflorum Decreases Airway Allergic Symptoms in a Murine Model of Asthma.
10.) Promotion effect of constituents from the root of Polygonum multiflorum on hair growth.
11.) Topical application of Polygonum multiflorum extract induces hair growth.
12.) Neuroprotective effects of Polygonum multiflorum extract against glutamate-induced oxidative toxicity.
16.) Hair Growth Promotion Activity and Its Mechanism of Polygonum multiflorum.
20.) Effect of compound Polygonum multiflorum extract on Alzheimer’s disease.
22.) An extract of Polygonum multiflorum protects against free radical damage.
24.) Polygonum multiflorum Extracts Improve Cognitive Performance.

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Immune Defence (Mushroom Blend)

Scientific Studies of different Superfood Mushrooms.

1.) The Pharmacological Potential of Mushrooms.
2.) Current findings, future trends, and unsolved problems in studies of medicinal mushrooms.
4.) Medicinal Mushrooms in Human Clinical Studies.
5.) Antitumor polysaccharides from mushrooms.
6.) Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides.
7.) Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms.
8.) Anti-inflammatory and immunomodulating properties of fungal metabolites.
9.) Hepatoprotective effects of mushrooms.
11.) Therapeutic potential of culinary-medicinal mushrooms for the management of neurodegenerative diseases.
12.) Medicinal mushrooms for glycemic control in diabetes mellitus.
14.) Immunomodulating and anticancer agents in the realm of macromycetes fungi.
15.) A review on antimicrobial activity of mushroom (Basidiomycetes) extracts and isolated compounds.
20.) Mushrooms, tumors, and immunity.
Find more scientific studies available at PubMed.

Lion's Mane Mushroom

Scientific Studies of Lion's Mane Mushroom (Hericium erinaceus).

1.) Nerve growth factor-inducing activity of Lion's Mane mushroom.
2.) Neuroregenerative potential of Lion's Mane mushroom in the treatment of peripheral nerve injury.
3.) Neurotrophic properties of Lion's Mane mushroom.
4.) Anti-cancer activities of Lion's Mane mushroom.
5.) Hericium erinaceus mushroom extracts inhibit metastasis of cancer cells.
6.) Hericium erinaceus on inhibition of human leukaemia cell line proliferation.
7.) Protective effects of Hericium erinaceus mycelium and its isolated erinacine A against ischemia-injury-induced cell death.
8.) Hericium erinaceus activates peripheral nerve regeneration.
9.) Hericium erinaceus mushroom-induced apoptosis of U937 human monocytic leukaemia cells.
10.) Gastroprotective Effects of Lion's Mane mushroom.
11.) Antioxidant activity of Lion's Mane mushroom.
12.) Antioxidant and Anti-Osteoporotic Activities of Hericium erinaceus.
13.) Anti-fatigue activities of polysaccharides extracted from Hericium erinaceus.
14.) Anti-Gastric Ulcer Activity of Polysaccharide Fraction Isolated from Mycelium Culture of Lion's Mane mushroom.
15.) Lion's Mane mushroom Stimulates Neurite Outgrowth in Dissociated Cells of Brain, Spinal Cord, and Retina.
16.) Neuronal Health and Lion's Mane mushroom.
17.) Lion's Mane mushroom and its protective effects on Aβ-Triggered Neurotoxicity in PC12 cells.
18.) Vitamin B12 content of the edible Lion's Mane mushroom fruiting body.
19.) Lion's Mane mushroom accelerates wound healing.

Find more scientific studies available at PubMed.


Maitake Mushroom

Scientific Studies of Maitake Mushroom (Grifola frondosa).

1.) Genes Related to Suppression of Malignant Phenotype Induced by Maitake D-Fraction in Breast Cancer Cells.
2.) Antitumor activity of orally administered maitake α-glucan by stimulating antitumor immune response in murine tumor.
3.) Maitake beta-glucan promotes recovery of leukocytes and myeloid cell function in peripheral blood from paclitaxel hematotoxicity.
4.) A polysaccharide extracted from Grifola frondosa enhances the anti-tumor activity of bone marrow-derived dendritic cell-based immunotherapy against murine colon cancer.
5.) Maitake extracts and their therapeutic potential.
6.) Grifola frondosa water extract alleviates intestinal inflammation by suppressing TNF-α production and its signaling.
7.) Possible immunotherapeutic potentiation with D-Fraction in prostate cancer cells.
8.) Anti-diabetic activity present in the fruit body of Grifola frondosa (Maitake).
9.) Maitake (Grifola frondosa) improve glucose tolerance of experimental diabetic rats.
10.) Can maitake MD-fraction aid cancer patients?
11.) Maitake beta-glucan MD-fraction enhances bone marrow colony formation and reduces doxorubicin toxicity in vitro.
12.) Anti-diabetic effect of an alpha-glucan from fruit body of maitake (Grifola frondosa) on KK-Ay mice.
13.) Inhibitory effect of MD-Fraction on tumor metastasis: involvement of NK cell activation and suppression of intercellular adhesion molecule (ICAM)-1 expression in lung vascular endothelial cells.
14.) A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: immunological effects.
15.) Antitumor effects of a water-soluble extract from Maitake (Grifola frondosa) on human gastric cancer cell lines.
16.) Maitake beta-glucan promotes recovery of leukocytes and myeloid cell function in peripheral blood from paclitaxel hematotoxicity.
17.) Synergistic potentiation of activity with maitake mushroom d-fraction on bladder cancer cells.
18.) Maitake mushroom (Grifola frondosa) extract induces ovulation in patients with polycystic ovary syndrome: a possible monotherapy and a combination therapy after failure with first-line clomiphene citrate.
19.) Maitake (D fraction) mushroom extract induces apoptosis in breast cancer cells by BAK-1 gene activation.
20.) Structure of a β-glucan from Grifola frondosa and its antitumor effect by activating Dectin-1/Syk/NF-κB signaling.

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Mucuna Pruriens

Scientific Studies of Mucuna Pruriens.

1.) Evaluation of the anti-diabetic properties of Mucuna pruriens seed extract.
2.) Effects of Mucuna pruriens on Free Fatty Acid Levels and Histopathological Changes in the Brains.
3.) Mucuna pruriens in Parkinson's disease: a double blind clinical and pharmacological study.
4.) Immunomodulation of Parkinson's disease using Mucuna pruriens.
5.) Mechanism of antihypertensive effect of Mucuna pruriens L. seed extract.
6.) Mucuna pruriens Reduces Stress and Improves the Quality of Semen in Infertile Men.
7.) Dopamine mediated antidepressant effect of Mucuna pruriens seeds in various experimental models of depression.
8.) The Magic Velvet Bean of Mucuna pruriens.
9.) In vitro and in vivo investigation of natural compounds from seed extract of Mucuna prurienslacking l-DOPA for the treatment of erectile dysfunction.
10.) Mucuna pruriens reduces inducible nitric oxide synthase expression in Parkinsonian mice model.
11.) Evaluation of Hypotensive and Antihypertensive Effects of Velvet Bean (Mucuna pruriens L.) Hydrolysates.
12.) Mucuna pruriens for Parkinson's disease.
13.) The hypolipidemic effect and antithrombotic activity of Mucuna pruriens.
14.) Mucuna pruriens in Parkinson Disease: A Kinetic-Dynamic Comparison With Levodopa Standard Formulations.
15.) Angiotensin-converting enzyme (ACE) inhibitory potential of standardized Mucuna pruriens seed extract.
16.) Antiproliferative effect of isolated isoquinoline alkaloid from Mucuna pruriens seeds in hepatic carcinoma cells.
17.) Mucuna pruriens seed extract reduces oxidative stress.
18.) Darkening of white hair in Parkinson's disease during use of levodopa rich Mucuna pruriens extract powder.
19.) Mucuna pruriens and its major constituent L-DOPA recover spermatogenic loss by combating ROS, loss of mitochondrial membrane potential and apoptosis.
20.) Evaluation of the anti-diabetic properties of Mucuna pruriens seed extract.
21.) Antiparkinson drug--Mucuna pruriens shows antioxidant and metal chelating activity.
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Mushroom Beet Latte

Scientific Studies of Chaga Mushroom (Inonotus obliquus).

1.) Immunostimulating Activity by Polysaccharides Isolated from Fruiting Body of Inonotus obliquus.
2.) Continuous intake of the Chaga mushroom (Inonotus obliquus) aqueous extract suppresses cancer progression and maintains body temperature in mice.
3.) Ergosterol peroxide from Chaga mushroom (Inonotus obliquus) exhibits anti-cancer activity by down-regulation of the β-catenin pathway in colorectal cancer.
4.) Anticancer effects of fraction isolated from fruiting bodies of Chaga medicinal mushroom.
5.) Antitumor activity and structure characterization of ethanol extracts from wild and cultivated Chaga medicinal mushroom.
6.) Alcohol extract of Chaga and its effects on colon cancer cells.
7.) Anticancer activity of subfractions containing pure compounds of Chaga mushroom (Inonotus obliquus) extract.
8.) Anticancer properties of the water extract of Inonotus [corrected] obliquus by induction of apoptosis in melanoma B16-F10 cells.
9.) Chaga mushroom extract inhibits oxidative DNA damage in lymphocytes of patients with inflammatory bowel disease.
10.) Immunomodulatory Activity of the Water Extract from Medicinal Mushroom Inonotus obliquus.
11.) Chaga and its anti-viral effects.
12.) Chaga and its anti-inflammatory effects.
13.) Aqueous extract of Inonotus obliquus ameliorates acute inflammation in dextran sulfate sodium (DSS)-induced colitis.
14.) Hepatoprotective Activity of Chaga.
15.) Anti-allergic Activity of Chaga.
16.) Anti-herpetic Activity of Chaga.

Find more scientific studies available at PubMed.


Mushroom Cacao Latte

Scientific Studies of Reishi Mushroom (Ganoderma lucidum).

1.) An Overview of Reishi Mushroom
2.) Reishi polysaccharides (beta 1/3,1/6 glucan) as an Immunomodulator in Inflammation.
3.) Reishi and Kidney Health.
4.) Reishi Improves Physical Fitness in Women with Fibromyalgia.
5.) Ganoderma lucidum inhibits cancer cell growth and expression of key molecules in inflammatory breast cancer.
6.) Anti-tumor effects of Ganoderma lucidum in inflammatory breast cancer in in vivo and in vitro models.
7.) Ganoderma lucidum inhibits tumour cell proliferation and induces tumour cell death.
8.) Study of Ganoderma lucidum polysaccharides in Patients with Advanced Lung Cancer.
9.) Reishi Modulates the Composition of Gut Microbiota and Reduces Obesity.
10.) Anti-inflammatory and antimicrobial effects of Reishi mushroom.

Find more scientific studies available at PubMed.


Mushroom Matcha Latte

Scientific Studies of Lion's Mane Mushroom (Hericium erinaceus).

1.) Nerve growth factor-inducing activity of Lion's Mane mushroom.
2.) Neuroregenerative potential of Lion's Mane mushroom in the treatment of peripheral nerve injury.
3.) Neurotrophic properties of Lion's Mane mushroom.
4.) Anti-cancer activities of Lion's Mane mushroom.
5.) Hericium erinaceus mushroom extracts inhibit metastasis of cancer cells.
6.) Hericium erinaceus on inhibition of human leukaemia cell line proliferation.
7.) Protective effects of Hericium erinaceus mycelium and its isolated erinacine A against ischemia-injury-induced cell death.
8.) Hericium erinaceus activates peripheral nerve regeneration.
9.) Hericium erinaceus mushroom-induced apoptosis of U937 human monocytic leukaemia cells.
10.) Gastroprotective Effects of Lion's Mane mushroom.
11.) Antioxidant activity of Lion's Mane mushroom.
12.) Antioxidant and Anti-Osteoporotic Activities of Hericium erinaceus.
13.) Anti-fatigue activities of polysaccharides extracted from Hericium erinaceus.
14.) Anti-Gastric Ulcer Activity of Polysaccharide Fraction Isolated from Mycelium Culture of Lion's Mane mushroom.
15.) Lion's Mane mushroom Stimulates Neurite Outgrowth in Dissociated Cells of Brain, Spinal Cord, and Retina.
16.) Neuronal Health and Lion's Mane mushroom.
17.) Lion's Mane mushroom and its protective effects on Aβ-Triggered Neurotoxicity in PC12 cells.
18.) Vitamin B12 content of the edible Lion's Mane mushroom fruiting body.
19.) Lion's Mane mushroom accelerates wound healing.

Find more scientific studies available at PubMed.


Mushroom Turmeric Latte

Scientific Studies of Mushroom Turmeric Latte (Cordyceps militaris, curcumin, ginger, black pepper, cinnamon).

1.) Song J, Wang Y, Teng M, Cai G, Xu H, Guo H, Liu Y, Wang D, Teng L (2015. Studies on the Antifatigue Activities of Cordyceps militaris Fruit Body Extract in Mouse Model. Evid Based Complement Alternat Med. 2015;2015:174616. doi: 10.1155/2015/174616.
2.) Katie R. Hirsch, Abbie E. Smith-Ryan, Erica J. Roelofs, Eric T. Trexler, and Meredith G. Mock (2016). Cordyceps militaris improves tolerance to high intensity exercise after acute and chronic supplementation. J Diet Suppl. : 1–13. doi: 10.1080/19390211.2016.1203386
3.) Liu XC, Zhu ZY, Liu YL, Sun HQ (2019). Comparisons of the anti-tumor activity of polysaccharides from fermented mycelia and cultivated fruiting bodies of Cordyceps militaris in vitro. Int J Biol Macromol. 2019 Feb 27;130:307-314. doi: 10.1016/j.ijbiomac.2019.02.155.
4.) Kunwar, A. & Priyadarsini (2016). Curcumin and its role in chronic diseases. Advances in Experimental Medicine and Biology, 928, 1-25. Doi:10.1007/978-3-319-41334-1 1
5.) Tang, Y. & Chen, A. (2014). Curcumin eliminates the effect of advanced glycation end-products (AGEs) on the divergent regulation of gene expression of receptors of AGEs by interrupting leptin signaling. Laboratory Investigation: a journal of technical methods and pathology, 94(5), 503-516. Doi:10.1038/labinvest.2014.42
6.) Tejada, S., Manayi, A., Daglia, M., Nabavi, S., Sureda, A., Hajheydari, Z., Gortzi, O., Pazoki-Toroudi, H., & Nabavi, S. (2016). Wound healing effects of curcumin: a short review. Current Pharmaceutical Biotechnology, 17(11), 1002-1007.
7.) Khatri, D. & Juvekar, A. (2016). Neuroprotective effect of curcumin as evinced by abrogation of rotenone-induced motor deficits, oxidative and mitochondrial dysfunctions in mouse model of Parkinson’s disease. Pharmocology, Biochemistry, and Behaviour, 150, 39-47. Doi:10.1016/j.pbb.2016.09.002
8.) Butt, M. Pasha, I., Sultan, M., Randhawa, M., Saeed, F. & Ahmed, W. (2013). Black pepper and health claims: a comprehensive treatise. Ciritcal Reviews in Food Science and Nutrition, 53(9), 875-886. Doi:10.1080/10408398.2011.571799
9.) Amri, M. & Touil-Boukoffa, C. (2016). In vitro anti-hydatic and immunomodulatory effects of ginger and [6]-gingerol. Asian Pacific Journal of Tropical Medicine, 9(8), 749-756. Doi:10.1016/j.apjtm.2016.06.013
10.) Kawatra, P. & Rajagopalan, R. (2015). Cinnamon: mystic powers of a minute ingredient. Pharmacognosy Research, 7(Suppl 1), S1-S6. Doi:10.4103/0974-8490.157990

Nettle Root

Scientific Studies of Nettle root (Urtica dioica).

1.) A comprehensive review on the stinging nettle effect and efficacy profiles.
2.) Aromatase Inhibitors from Urtica dioica Roots.
3.) The Effect of Extracts of the Roots of the Stinging Nettle (Urtica dioica) on the Interaction of SHBG with its Receptor on Human Prostatic Membranes.
4.) Lignans from the Roots of Urtica dioica and their Metabolites Bind to Human Sex Hormone Binding Globulin (SHBG).
5.) Plant constituents interfering with human sex hormone-binding globulin.
6.) Efficacy and safety of a combination of Sabal and Urtica extract in lower urinary tract symptoms.
7.) Stinging nettle root extract (Bazoton-uno) in long term treatment of benign prostatic syndrome (BPS).
8.) Urtica dioica for Treatment of Benign Prostatic Hyperplasia.
9.) Cardiovascular effects of Urtica dioica L. (Urticaceae) roots extracts: in vitro and in vivo pharmacological studies.
10.) Antiproliferative Effect on Human Prostate Cancer Cells by a Stinging Nettle Root (Urtica dioica) Extract.
Find more scientific studies available at PubMed.

Pearl Powder

Scientific Studies of Pearl (Hyriopsis cumingii).

  1. Chen, H., Chang, J., Wu, J. (2008). Calcium Bioavailability of Nanonized Pearl Powder for Adults. Journal of Food Science, 73(9).
  2. Vujasinovic-Stupar, N., Novkovic, S., Jezdic, I. (2008). Supplementation with Bio-Calcium from Shells Pinctada Maxima in Patients with Decreased Bone Mineral Density. Bone, 43.
  3. Flausse, A. et al. (2013). Osteogenic differentiation of human bone marrow mesenchymal stem cells in hydrogel containing nacre powder. Journal of Biomedical Materials Research Part A.
  4. Liu, Y., Huang, Q., Feng, Q. (2013). 3D scaffold of PLLA/pearl and PLLA/nacre powder for bone regeneration. Biomedical Materials, 8(6), 065001.
  5. Yunyi Zhang, Wenwu Gu, Xinrui Zhong. The Pharmacology and Effects of Water Soluble Pearl on Heart Functions. Chinese medicine 16(9): 35, 1994
  6. Shao, D., Wang, C. et al. (2010). Abstracts: Comparison of hydration, tyrosinase resistance, and antioxidant activation in three kinds of pearl powders. International Journal of Cosmetic Science, 32(5), 396-396.
  7. Kangmin Gong, Yuanlong Zheng, Liping Hu, Xueyan Tao. The healing effects of Pearl on 90 seniors with high blood pressure. The Zhejiang Traditional Chinese Medicine Journal 456 2000
  8. Huang S. The effect of pearl on children with mental disabilities. Journal of Chinese Herbal Medicine 1976, 8:22
  9. Li, Y., Chen, C., Young, T. (2012). Pearl extract enhances the migratory ability of fibroblasts in a wound healing model. Pharmaceutical Biology, 51(3), 289-297.
  10. Jian-Ping, D., et al. (2009). Effects of pearl powder extract and its fractions on fibroblast function relevant to wound repair. Pharmaceutical Biology, 48(2), 122-127.
  11. Wanfu Li. The clinical study of using pearl formula to treat chronic skin ulcer. Gansu Chinese Medicine Journal, 8(2): 10,1997

Pine Pollen

Scientific Studies of Pine Pollen (Pinus pollen).

1.) A study on the nutritive value of pollen from the Chinese Masson Pine (Pinus massoniana) and its effect on fecal characteristics in rats.
2.) Effect of pine pollen on kidney mitochondria DNA deletion mutation in senile mice.
3.) Antioxidant and antiinflammatory activity of pine pollen extract in vitro.
4.) Testosterone, epitestosterone and androstenedione in the pollen of scotch pine.
5.) Effect of pine pollen extract on experimental chronic arthritis.
6.) Antinociceptive and antiinflammatory activities of pine (Pinus densiflora) pollen extract.
7.) Vitamin D and its metabolites in the pollen of pine. (n.d.). Steroid Hormones in the Pollen of Pine Species, part 5.
8.) Immunomodulatory effects of sulfated polysaccharides of pine pollen on mouse macrophages.
9.) Effects of sulfated polysaccharide from Masson pine (Pinus massoniana) pollen on the proliferation and cell cycle of HepG2 cells.
10.) Antiaging effect of pine pollen in human diploid fibroblasts and in a mouse model induced by D-galactose.
11.) Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning.

Polyrhachis Ant

Scientific Studies of Polyrhachis Ant (Polyrhachis vicina roger).

1.) Nutritional composition of Polyrhachis vicina Roger (Edible Chinese black ant).
2.) The effects of Polyrhachis vicina on immunoregulation in mice.
3.) The treatment of intrauterine growth retardation with ant polyrhachis vicina roger.

Qi/Chi Tonic Herbs

Scientific Studies of Chinese Tonic Herbs.

1.) Enhancement of ATP generation capacity, antioxidant capacity, and immunomodulatory activities by Chinese Yang and Yin tonifying herbs.
2.) Chinese Herbal Medicine on Cardiovascular Diseases.
3.) An in vitro study of neuroprotective properties of traditional Chinese herbal medicines thought to promote healthy ageing and longevity.
4.) Cytoprotective properties of traditional Chinese medicinal herbal extracts in hydrogen peroxide challenged human U373 astroglia cells.
5.) In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms.
6.) Traditional Chinese Medicine (TCM) and Herbal Hepatotoxicity.
7.) Efficacy and Safety of Chinese Medicinal Herbs for the Treatment of Hyperuricemia.
8.) Chinese Herbal Medicines for the Treatment of Type A H1N1 Influenza.
9.) Chinese Herbal Medicine Treatment Improves the Overall Survival Rate of Individuals with Hypertension among Type 2 Diabetes Patients.
10.) Inhibitory effects of Chinese nutritional herbs in isogenic breast carcinoma cells with modulated estrogen receptor function.
Find more scientific studies available at PubMed.

Jing Tonic Herbs

Scientific Studies of Chinese Tonic Herbs.

1.) Enhancement of ATP generation capacity, antioxidant capacity, and immunomodulatory activities by Chinese Yang and Yin tonifying herbs.
2.) Chinese Herbal Medicine on Cardiovascular Diseases and the Mechanisms of Action.
3.) An in vitro study of neuroprotective properties of traditional Chinese herbal medicines thought to promote healthy ageing and longevity.
4.) Cytoprotective properties of traditional Chinese medicinal herbal extracts in hydrogen peroxide challenged human U373 astroglia cells.
5.) In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms.
6.) TSG (2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside) from the Chinese Herb Polygonum multiflorum Increases Life Span and Stress Resistance of Caenorhabditis elegans.
7.) Traditional Chinese Medicine (TCM) and Herbal Hepatotoxicity: RUCAM and the Role of Novel Diagnostic Biomarkers Such as MicroRNAs.
8.) Efficacy and Safety of Chinese Medicinal Herbs for the Treatment of Hyperuricemia: A Systematic Review and Meta-Analysis.
9.) Chinese Herbal Medicines for the Treatment of Type A H1N1 Influenza: A Systematic Review of Randomized Controlled Trials.
10.) Chinese Herbal Medicine Treatment Improves the Overall Survival Rate of Individuals with Hypertension among Type 2 Diabetes Patients and Modulates In Vitro Smooth Muscle Cell Contractility.
11.) Inhibitory effects of Chinese nutritional herbs in isogenic breast carcinoma cells with modulated estrogen receptor function.
Find more scientific studies available at PubMed.

Reishi Mushroom

Scientific Studies of Reishi Mushroom (Ganoderma lucidum).

1.) An Overview of Reishi Mushroom
2.) Reishi polysaccharides (beta 1/3,1/6 glucan) as an Immunomodulator in Inflammation.
3.) Reishi and Kidney Health.
4.) Reishi Improves Physical Fitness in Women with Fibromyalgia.
5.) Ganoderma lucidum inhibits cancer cell growth and expression of key molecules in inflammatory breast cancer.
6.) Anti-tumor effects of Ganoderma lucidum in inflammatory breast cancer in in vivo and in vitro models.
7.) Ganoderma lucidum inhibits tumour cell proliferation and induces tumour cell death.
8.) Study of Ganoderma lucidum polysaccharides in Patients with Advanced Lung Cancer.
9.) Reishi Modulates the Composition of Gut Microbiota and Reduces Obesity.
10.) Anti-inflammatory and antimicrobial effects of Reishi mushroom.

Find more scientific studies available at PubMed.


Schizandra Berry

Scientific Studies of Schizandra Berry (Schisandra chinensis).

1.) Improvement of liver function in humans using schisandra fruit extract.
2.) Schisandra chinensis prevents alcohol-induced fatty liver disease in rats.
4.) Anti-inflammatory Effects of Schisandra chinensis.
5.) Anti-inflammatory effects of schisandrin isolated from the fruit of Schisandra chinensis Baill.
6.) Antioxidant and hepatoprotective effects of Schisandra chinensis.
7.) Effects of Selenylation Modification on Antioxidative Activities of Schisandra chinensis Polysaccharide.
8.) Schisandra chinensis produces the antidepressant-like effects.
9.) The effect of Schisandra chinensis extracts on depression.
10.) Schisandra Chinensis Alleviates High-Fat-Diet-Inducing Non-Alcoholic Steatohepatitis in Rats.
11.) Schisandra chinensis reverses visceral hypersensitivity in a neonatal-maternal separated rat model.
12.) Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protective Activity.
14.) Effect of Schisandra chinensis on interleukins, glucose metabolism, and pituitary-adrenal and gonadal axis in rats under strenuous swimming exercise.
15.) Stimulating effect of adaptogens: an overview with particular reference to their efficacy following single dose administration.
16.) Lignans from Schisandra chinensis ameliorate cognition deficits and attenuate brain oxidative damage induced by D-galactose in rats.
17.) Effects of Schisandra chinensis extract on gastrointestinal motility in mice.
18.) Comparative studies on polyphenolic composition, antioxidant and antimicrobial activities of Schisandra chinensis leaves and fruits.
20.) The immuno-regulatory effects of Schisandra chinensis and its constituents on human monocytic leukemia cells.
25.) Structural identification and antioxidant properties of major anthocyanin extracted from Omija (Schizandra chinensis) fruit.
26.) In vitro and in vivo anti-hyperglycemic effects of Omija (Schizandra chinensis) fruit.
27.) Improvement of liver function in humans using a mixture of schisandra fruit extract and sesamin.
28.) Treatment of chronic hepatitis C virus infection via antioxidants.
30.) Antitumor and immunomodulatory activity of a water-soluble low molecular weight polysaccharide from Schisandra chinensis.
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Tremella Mushroom

Scientific Studies of Tremella Mushroom (Tremella fuciformis).

1.) Characterisation of acidic heteroglycans from Tremella fuciformis Berk with cytokine stimulating activity.
2.) Efficacy and Safety of Tremella fuciformis in Individuals with Subjective Cognitive Impairment: A Randomized Controlled Trial.
3.) Tremella fuciformis polysaccharide suppresses hydrogen peroxide-triggered injury of human skin fibroblasts via upregulation of SIRT1.
4.) Protective effect of Tremella fuciformis Berk extract on LPS-induced acute inflammation via inhibition of the NF-κB and MAPK pathways.
5.) Comparison of Immunomodulatory and Anticancer Activities in Different Strains of Tremellafuciformis Berk.
6.) Studies on the purification of polysaccharides separated from Tremella fuciformis and their neuroprotective effect.
7.) Protective effect of polysaccharides isolated from Tremella fuciformis against radiation-induced damage in mice.
8.) Effect of Tremella fuciformis on the neurite outgrowth of PC12h cells and the improvement of memory in rats.
9.) The Neuroprotective and Neurotrophic Effects of Tremella fuciformis in PC12h Cells.
10.) Characterisation of acidic heteroglycans from Tremella fuciformis Berk with cytokine stimulating activity.

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Turkey Tail Mushroom

Scientific Studies of Turkey Tail Mushroom (Trametes versicolor or Coriolus versicolor).

1.) Effects of polysaccharopeptide from Trametes versicolor and amoxicillin on the gut microbiome of healthy volunteers: a randomized clinical trial.
2.) Trametes versicolor extract modifies human fecal microbiota composition in vitro.
3.) Cytotoxic activities of Coriolus versicolor (Yunzhi) extract on human leukaemia and lymphoma cells by induction of apoptosis.
4.) Efficacy of immunochemotherapy as adjuvant treatment after curative resection of gastric cancer. Study Group of Immunochemotherapy with PSK for Gastric Cancer.
5.) Postoperative adjuvant immunochemotherapy with mitomycin C, futraful and PSK for gastric cancer. An analysis of data on 579 patients followed for five years.
6.) Significant prolongation of disease-free period gained by oral polysaccharide K (PSK) administration after curative surgical operation of colorectal cancer.
7.) Coriolus versicolor polysaccharide peptide slows progression of advanced non-small cell lung cancer.
8.) Immunomodulatory activities of Yunzhi and Danshen in post-treatment breast cancer patients.
9.) A randomized trial of chemoimmunotherapy of acute nonlymphocytic leukemia in adults using a protein-bound polysaccharide preparation.
10.) The cell death process of the anticancer agent polysaccharide-peptide (PSP) in human promyelocytic leukemic HL-60 cells.
11.) Anticancer effects and mechanisms of polysaccharide-K (PSK): implications of cancer immunotherapy.
12.) Polysaccharopeptides of Coriolus versicolor: physiological activity, uses, and production.

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